Effect Of Standard Versus Restricted Fluid Therapy Guided By Electric Cardiometry On Tissue Perfuison In Robotic Prostaectomy A Randomized Controlled Study

DecenTrialz · Cairo, Egypt · Posted 2026-07-11

Actively RecruitingPhase Not ApplicableAge: 40Years - 80YearsMALEID07626151Effect Of Standard Versus Restricted Fluid Therapy Guided By Electric Cardiometry On Tissue Perfuison In Robotic Prostaectomy A Randomized Controlled StudyLed by Nazmy Edward Seif Updated on 2026-06-0890Participants Needed1Research SitesN/ATotal DurationOn this pageAI-SummaryBrief TitleWho Can ParticipateAI-ScreeningTrial Site LocationsResearch TeamHow is the study designed?Similar TrialsAI-SummaryWhat This Trial Is AboutFluid therapy during surgery is an important factor that is related to long term mortality and morbidity and it's directly related to tissue perfusion as well. The main target in any surgery is what is the optimum fluid therapy to maintain the tissue perfusion and the precise balance between hazardous effects of hypervolemia that may cause delayed wound healing due to surgical anastomosis disruption or being hypovolemic that may cause tissue ischemia as acute kidney injury. Fluid management guidance changed from static methods like central venous pressure into dynamic methods like pulse pressure variation (PPV) and stroke volume variation (SVV), which are now the most famous dynamic measures. Electrical cardiometry is a non-invasive cardiac output monitor which uses electrical cardiometry, now a commonly used device, to measure SVV which can be used to guide fluid therapy during surgeries. Now robotic assisted surgery is a common method in preforming many surgeries especially urological, since it's associated with numerous desirable outcomes including shorter post-operative stay and faster return to preoperative function. With considerations related to severe Trendelenburg position and increased intra-abdominal pressure due to pneumo-peritoneum, robotic assisted surgeries are associated with many challenges in anesthesia especially the fluid therapy. Fluid therapy in robotic surgeries is an area with growing research focus that need further exploration while there are established guidelines for fluid management in traditional surgeries, the optimal protocols for robotic surgeries are less well defined, needing more research. We aim at this study to investigate the impact of liberal versus restricted fluid intake on the tissue perfusion reflected by serum lactate \& creatinine clearance, while guiding therapy through electrical cardiometry, to reach optimum fluid protocol in prostatic robotic surgeries.CONDITIONSBrief TitleElectric Cardiometry-Guided Standard Versus Restricted Fluid Therapy In Robotic ProstaectomyWho Can ParticipateAge: 40Years - 80YearsMALEEligibility CriteriaInclusion CriteriaMale patient undergoing robotic assisted prostatectomyASA I-IIIExclusion CriteriaASA score more than IIIBMI more than 40Severe renal disease (GFR between 15 and 29)Previous renal surgery.Decompensated cardiac disease (NYHA class 3 or 4)AI-ScreeningAI-Powered ScreeningComplete this quick 3-step screening to check your eligibility123First name *Last name *Email Address *Phone Number *+1Gender*ZIP Code *I agree to receive SMS messages from DecenTrialz regarding trial matching, appointment updates, participant updates, and related information. Message frequency varies. Message & data rates may apply. Reply STOP to cancel or HELP for assistance. I also agree to the Terms of Service and Privacy Policy.*Trial Site LocationsTotal: 1 location1Cairo University HospitalsCairo, EgyptActively RecruitingLoading map...Research TeamMMohamed M Mohamed, M.Sc.NNazmy S Mikhael, M.D.How is the study designed?Study TypeINTERVENTIONALMaskingDOUBLEAllocationRANDOMIZEDModelPARALLELPrimary PurposeSUPPORTIVE_CARENumber of Arms2Not the Right Trial for You?Explore thousands of other clinical trials that might be a better match.Sign up to get personalized trial recommendations delivered to your inbox.Already have an account? Log in hereOn this pageAI-SummaryBrief TitleWho Can ParticipateAI-ScreeningTrial Site LocationsResearch TeamHow is the study designed?Similar TrialsSponsorsNNazmy Edward SeifLead Sponsor

Apply for this role

Other open roles at DecenTrialz

See all 5 open roles at DecenTrialz →

Related jobs in Other